{"id":8042,"date":"2022-12-10T00:00:00","date_gmt":"2022-12-09T23:00:00","guid":{"rendered":"https:\/\/instrid.sk\/uncategorized\/co-sposobuje-parkinsonovu-chorobu-4-hlavne-rizikove-faktory\/"},"modified":"2022-12-10T00:00:00","modified_gmt":"2022-12-09T23:00:00","slug":"co-sposobuje-parkinsonovu-chorobu-4-hlavne-rizikove-faktory","status":"publish","type":"post","link":"https:\/\/instrid.sk\/en\/archiv\/co-sposobuje-parkinsonovu-chorobu-4-hlavne-rizikove-faktory\/","title":{"rendered":"\u010co sp\u00f4sobuje Parkinsonovu chorobu? 4 hlavn\u00e9 rizikov\u00e9 faktory"},"content":{"rendered":"

Nikto presne nevie, \u010do sp\u00f4sobuje Parkinsonovu chorobu, ale m\u00f4\u017ee to by\u0165 d\u00f4sledok v\u00e1\u0161ho veku, prostredia, genetiky a \u010fal\u0161\u00edch faktorov.<\/p>\n

Parkinsonova choroba sa vyskytuje vtedy, ke\u010f mozgov\u00e9 bunky zodpovedn\u00e9 za produkciu dopam\u00ednu, chemick\u00e9ho posla, ktor\u00fd koordinuje svalov\u00e9 pohyby a reakcie tela, prestan\u00fa pracova\u0165<\/strong> alebo odumr\u00fa.<\/p>\n

Zvy\u010dajne vedie k motorick\u00fdm sympt\u00f3mom, ako je tremor, stuhnutos\u0165 a spomalen\u00fd pohyb<\/strong>.<\/p>\n

M\u00f4\u017ee tie\u017e vies\u0165 k \u010fal\u0161\u00edm pr\u00edznakom, ako je \u00fazkos\u0165 a depresia<\/strong>.<\/p>\n

Strata nervov\u00fdch buniek je pomal\u00fd proces. Pr\u00edznaky Parkinsonovej choroby sa zvy\u010dajne za\u010d\u00ednaj\u00fa prejavova\u0165 a\u017e vtedy, ke\u010f sa strat\u00ed pribli\u017ene 50 % aktivity nervov\u00fdch buniek.<\/strong><\/p>\n

Ale napriek tomu, \u017ee o pr\u00edznakoch tejto choroby ve\u013ea vieme, st\u00e1le zost\u00e1va jedna ve\u013ek\u00e1 ot\u00e1zka: \u010co presne sp\u00f4sobuje Parkinsonovu chorobu?<\/strong><\/p>\n

Bohu\u017eia\u013e, na to neexistuje jednoduch\u00e1 odpove\u010f.<\/p>\n

Neexistuje jedna pr\u00ed\u010dina, ale na z\u00e1klade toho, \u010do \u013eudstvo pre\u0161tudovalo, vieme, \u017ee Parkinsonova choroba vznik\u00e1 v d\u00f4sledku interakcie medzi starn\u00facim mozgom, va\u0161ou genetikou a prostred\u00edm<\/strong>.<\/p>\n

 <\/p>\n Zdrav\u00fd mozog vs. mozog s Parkinsonom. Zdroj: neurochallenge.org\n

 <\/p>\n

Faktory<\/h3>\n

 <\/p>\n

Vek<\/h3>\n

Vek priamo nesp\u00f4sobuje Parkinsonovu chorobu, ale starnutie je najv\u00e4\u010d\u0161\u00edm rizikov\u00fdm faktorom<\/strong> tejto neurologickej poruchy.<\/p>\n

Jedn\u00fdm z vysvetlen\u00ed je, \u017ee mozgov\u00e9 bunky s\u00fa \u010dasom n\u00e1chylnej\u0161ie na zranenie<\/strong>, rovnako ako zvy\u0161ok \u013eudsk\u00e9ho tela.<\/p>\n

\u010eal\u0161\u00edm je, \u017ee g\u00e9nov\u00e1 expresia \u2013 v podstate sp\u00f4sob, ak\u00fdm \u013eudsk\u00e9 g\u00e9ny funguj\u00fa \u2013 sa m\u00f4\u017ee \u010dasom meni\u0165 a sp\u00fa\u0161\u0165a\u0165 zmeny v bunkovej aktivite, ktor\u00e9 v kone\u010dnom d\u00f4sledku ved\u00fa k Parkinsonovej chorobe.<\/p>\n

Zvy\u010dajne s\u00fa \u013eudia s Parkinsonovou chorobou diagnostikovan\u00ed vo veku 60 rokov, a pravdepodobnos\u0165 sa zvy\u0161uje s vekom.<\/p>\n

V\u017edy v\u0161ak existuje mo\u017enos\u0165, \u017ee sa u niekoho vyvinie Parkinsonova choroba so skor\u00fdm n\u00e1stupom<\/strong>.<\/p>\n

V t\u00fdchto pr\u00edpadoch, ktor\u00e9 predstavuj\u00fa odhadom 4 % diagnostikovanej popul\u00e1cie, je pravdepodobnej\u0161ie, \u017ee ochorenie s\u00favis\u00ed s genetikou<\/strong>.<\/p>\n

 <\/p>\n

Genetika<\/h3>\n

Parkinsonova choroba sa m\u00f4\u017ee vyskytova\u0165 v rodin\u00e1ch v d\u00f4sledku toho, \u017ee chybn\u00e9 g\u00e9ny odovzdaj\u00fa die\u0165a\u0165u ich rodi\u010dia, no je zriedkav\u00e9, \u017ee sa choroba takto zded\u00ed<\/strong>.<\/p>\n

Genetika sp\u00f4sobuje Parkinsonovu chorobu asi v 10 a\u017e 15 % pr\u00edpadov<\/strong>.<\/p>\n

Genetick\u00fd v\u00fdskum je v\u0161ak st\u00e1le v plienkach, tak\u017ee odborn\u00edci e\u0161te nemaj\u00fa \u00fapln\u00fd obraz o \u00falohe g\u00e9nov.<\/p>\n

 <\/p>\n

 <\/p>\n

\u017divotn\u00e9 prostredie a \u017eivotn\u00fd \u0161t\u00fdl<\/h3>\n

Prostredie, v ktorom \u017eijete, m\u00f4\u017ee tie\u017e potenci\u00e1lne sp\u00f4sobi\u0165 Parkinsonovu chorobu, alebo zv\u00fd\u0161i\u0165 riziko.<\/p>\n

Ak\u00e9 je va\u0161e povolanie? Kde b\u00fdvate? Boli ste vystaven\u00ed nejak\u00fdm tox\u00ednom?<\/p>\n

Hoci odborn\u00edci nezistili presn\u00fa s\u00favislos\u0165 medzi tak\u00fdmito environment\u00e1lnymi faktormi a pr\u00ed\u010dinou Parkinsonovej choroby, d\u00f4kazy nazna\u010duj\u00fa, \u017ee m\u00f4\u017eu hra\u0165 \u00falohu pri rozvoji choroby.<\/p>\n

Existuj\u00fa ur\u010dit\u00e9 tox\u00edny, u ktor\u00fdch sa uk\u00e1zalo, \u017ee zvy\u0161uj\u00fa riziko<\/strong> Parkinsonovej choroby.<\/p>\n

Podobne aj ur\u010dit\u00e9 kovy<\/strong> m\u00f4\u017eu zv\u00fd\u0161i\u0165 riziko Parkinsonovej choroby. Predpoklad\u00e1 sa, \u017ee aj pestic\u00eddy a herbic\u00eddy pou\u017e\u00edvan\u00e9 v po\u013enohospod\u00e1rstve a doprave, alebo priemyseln\u00e9 zne\u010distenie, m\u00f4\u017eu prispie\u0165 k tomuto stavu.<\/p>\n

Vedci tie\u017e sk\u00famali, \u010di traumatick\u00e9 poranenia mozgu alebo otrasy mozgu m\u00f4\u017eu sp\u00f4sobi\u0165 Parkinsonovu chorobu – zistili, \u017ee len jeden otras mozgu m\u00f4\u017ee zv\u00fd\u0161i\u0165 riziko Parkinsonovej choroby o 57%<\/strong>.<\/p>\n

 <\/p>\n

In\u00e9 pr\u00ed\u010diny parkinsonizmu<\/h3>\n

\u201eParkinsonizmus\u201c je zastre\u0161uj\u00faci term\u00edn pou\u017e\u00edvan\u00fd na opis sympt\u00f3mov tras, svalovej stuhnutosti a spomalenia pohybu.<\/p>\n

Parkinsonova choroba je najbe\u017enej\u0161\u00edm typom parkinsonizmu, existuj\u00fa v\u0161ak aj zriedkavej\u0161ie typy, pri ktor\u00fdch mo\u017eno identifikova\u0165 \u0161pecifick\u00fa pr\u00ed\u010dinu<\/strong>.<\/p>\n

Patr\u00ed sem parkinsonizmus sp\u00f4soben\u00fd:<\/p>\n

    \n
  • liekmi<\/strong> (liekom vyvolan\u00fd parkinsonizmus) \u2013 ke\u010f sa sympt\u00f3my vyvin\u00fa po u\u017eit\u00ed ur\u010dit\u00fdch liekov\u00a0\u2013 konkr\u00e9tne t\u00fdch, ktor\u00e9 blokuj\u00fa p\u00f4sobenie dopam\u00ednu \u2013 m\u00f4\u017ee to sp\u00f4sobi\u0165 pr\u00edznaky Parkinsonovej choroby.Tu s\u00fa niektor\u00e9 z liekov, ktor\u00e9 m\u00f4\u017eu sp\u00f4sobi\u0165 pr\u00edznaky Parkinsonovej choroby:– Antipsychotik\u00e1<\/strong>
    \n-Lieky proti nevo\u013enosti\u00a0<\/strong>
    \n-Lieky, ktor\u00e9 lie\u010dia poruchy hyperkinetick\u00e9ho pohybu\u00a0<\/strong><\/p>\n

    Majte na pam\u00e4ti, \u017ee aj ke\u010f tieto lieky (a in\u00e9) m\u00f4\u017eu sp\u00f4sobi\u0165 pr\u00edznaky podobn\u00e9 Parkinsonovej chorobe, nesp\u00f4sobuj\u00fa samotn\u00fa chorobu. A v\u00e4\u010d\u0161inou pr\u00edznaky zmizn\u00fa v priebehu nieko\u013ek\u00fdch hod\u00edn alebo dn\u00ed<\/strong>, ke\u010f prestanete u\u017e\u00edva\u0165 tento liek.<\/p>\n

    V niektor\u00fdch pr\u00edpadoch pr\u00edznaky Parkinsonovej choroby nezmizn\u00fa, ke\u010f osoba prestane u\u017e\u00edva\u0165 lieky, ktor\u00e9 k nim viedli, a nakoniec sa u nich diagnostikuje Parkinsonova choroba.<\/li>\n<\/ul>\n

     <\/p>\n

      \n
    • in\u00e9 progres\u00edvne mozgov\u00e9 stavy<\/strong> \u2013 ako je progres\u00edvna supranukle\u00e1rna obrna, mnohopo\u010detn\u00e1 syst\u00e9mov\u00e1 atrofia a kortikobaz\u00e1lna degener\u00e1cia<\/li>\n<\/ul>\n

       <\/p>\n

        \n
      • cerebrovaskul\u00e1rne ochorenie<\/strong> \u2013 kde s\u00e9ria mal\u00fdch mozgov\u00fdch pr\u00edhod sp\u00f4sob\u00ed odumretie nieko\u013ek\u00fdch \u010dast\u00ed mozgu<\/li>\n<\/ul>\n

         <\/p>\n

        Parkinsonovu chorobu sp\u00f4sobuje kombin\u00e1cia g\u00e9nov, vplyvov prostredia a \u017eivotn\u00e9ho \u0161t\u00fdlu. S\u00fahra v\u0161etk\u00fdch troch zlo\u017eiek rozhoduje o tom, \u010di sa u niekoho vyvinie Parkinsonova choroba.<\/p>\n

        V\u00fdskum toho, \u010do sp\u00f4sobuje Parkinsonovu chorobu, neust\u00e1le rastie. Ak poci\u0165ujete pr\u00edznaky Parkinsonovej choroby, ako je chvenie r\u00fak, spomalen\u00fd pohyb, probl\u00e9my s rovnov\u00e1hou alebo zmeny vo va\u0161ej re\u010di alebo p\u00edsan\u00ed, spojte sa s lek\u00e1rom<\/strong> a diagnostikujte stav.<\/p>","protected":false},"excerpt":{"rendered":"

        Nikto presne nevie, \u010do sp\u00f4sobuje Parkinsonovu chorobu, ale m\u00f4\u017ee to by\u0165 d\u00f4sledok v\u00e1\u0161ho veku, prostredia, genetiky a \u010fal\u0161\u00edch faktorov. Parkinsonova choroba sa vyskytuje vtedy, ke\u010f<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-8042","post","type-post","status-publish","format-standard","hentry","category-archiv","two-columns"],"_links":{"self":[{"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/posts\/8042","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/comments?post=8042"}],"version-history":[{"count":0,"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/posts\/8042\/revisions"}],"wp:attachment":[{"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/media?parent=8042"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/categories?post=8042"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/instrid.sk\/en\/wp-json\/wp\/v2\/tags?post=8042"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}